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In breast cancer cells, caudatin enhanced TRAIL-induced apoptosis by boosting DR5 expression through a CHOP (C/EBP homologous protein)-dependent pathway along with sustained p38 MAPK and JNK signaling (Table 1, Row 6)

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Udy GB, Towers RP, Snell RG, Wilkins RJ, Park SH, Ram PA, Waxman DJ, Davey HW