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Voluma is a very stiff, bouncy, lifting filler and that could create problems in 2 ways: Voluma could become visible through the thinner-than-usual skin under the eyes, creating weird lumps and bumps (this is why Voluma is injected deep into tissues of the face and never superficially) Voluma creates lift in the areas where its injected - and too much lift under the eyes could create a puffy, unnatural look Now, sometimes you will see the undereye of a patient improve after having had Voluma injected, but that Voluma is injected into the cheeks

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5-Amino-1MQ, or 5-amino-1-methylquinoline, has emerged as a fascinating player in this arena

Antagonism with calcium ions is possible